Planar carboxylated surface utilizing an ethylene oxide coating – 采用环氧乙烷涂层的平面羧基化学修饰表面
General purpose surface useful for a wide range of interaction using various immobilization techniques – 常用的化学修饰表面,广泛应用于各种生物分子相互作用键合技术
Coupling of the ligand to the surface is normally achieved via amine coupling (EDC/NHS chemistry) – 通过胺偶联(碳化二亚胺/N-羟基琥珀酰亚胺)实现配体和化学修饰表面的偶联
Alternative methods such as thiol coupling, disulfide exchange and hydrazide coupling may also be employed – 亦可采用胺偶联外的其他方法,如巯基偶联,二硫键交换和肼偶联
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COOH2
Planar carboxylated surface utilizing a short polysaccharide coating – 采用短链多糖涂层的平面羧基化学修饰表面
General purpose surface similar to COOH1 in applications but may have different characteristics related to non-specific binding – 常用的化学修饰表面,用途与COOH1化学修饰表面类似,但与COOH1在非特异性结合特性上有所不同
In some applications, this surface may reduce non-specific binding when compared to the standard COOH surface chemistry – 在某些应用中,这种化学修饰表面可以减少非特异性结合的产生
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HiCap
Three dimensional polysaccharide chemistry – 采用多糖的三维化学修饰表面
Ideally suited for higher capacity ligand binding – 非常适用于较高能力的配体结合
Ideal for amine coupling of small peptides, drugs and other small molecules that possess amine groups – 理想的小分子肽,药物和其他含有胺基的小分子的胺偶联化学修饰表面
This surface is uncharged and confers high resistance to non-specific binding – 这种化学修饰表面不带电荷,并富有极强地对抗非特异性结合的特性
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BioCap
A two dimensional surface with neutravidin covalently attached to the surface – 采用中性链亲和素共价结合的二维化学修饰表面
Useful when coupling biotinylated ligands to the sensor surface such as oligonucleotides – 常用于偶联如寡核苷酸等生物素配体至传感器表面
It is ideal for the capture of biotinylated reagents including peptides, oligonucleotides, proteins and sugars in a non-reversible manner – 非常适合于生物素试剂非可逆方式捕获,包括多肽,寡核苷酸,蛋白质和糖类
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AvCap
A two dimensional surface with biotin covalently attached to the surface – 采用生物素共价结合的二维化学修饰表面
Useful when coupling avidin conjugated ligands to the sensor surface – 常用于偶联亲和素结合配体至传感器表面
It is a non-charged thereby limiting non-specific binding when compared to other negatively charged surfaces – 不带电荷表面,和其它带负电荷的表面相比,限制了非特异性结合
It provides high capacity immobilization and is ideal for acidic proteins or where high binding capacity is required – 提供高能力键合,zei适用于酸性蛋白或需要高结合能力的化学修饰表面
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AvHiCap
A three dimensional polysaccharide surface with biotin covalently attached to the polymer – 采用多糖并带有生物素共价结合至聚合物的三维化学修饰表面
Similar to AvCap surface but can be used when the immobilization of a higher capacity of avidin-conjugated ligand is required – 类似于AvCap化学修饰表面,但可用于键合需要更高结合能力的亲和素结合配体
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HisCap
A two dimensional prgylated surface that is modified with the Ni-NTA complex – 采用带有镍-NTA复合物的二维化学修饰表面
Used for capture of histidine-tagged ligands through chelation of imidazole groups to Ni – 常用于通过咪唑基团和至镍的螯合而捕获组氨酸标签配体
It is ideal for reversible capture of polyhistidine-tagged recombinant proteins – 理想的可逆性捕获多组氨酸标签重组蛋白的化学修饰表面
Immobilized proteins may be removed by exposure to imidazole allowing the surface to be re-coated – 通过暴露于咪唑除去键合的蛋白质后,传感器表面可被重新涂膜
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VesCap
A planar polyethylene glycol surface with decylamine hydrocarbon chains to anchor the membrane – 采用癸胺烃链锚固的平面聚乙二醇化学修饰表面
Coupling of liposomes, vesicles, membranes, and cells – 用于偶联脂质体、微囊、膜和细胞
Liposomes, unilamellar vesicles and even crude membrane preparations may be conveniently immobilized in a single step – 脂质体、单层囊泡、甚至膜均可被方便地一步键合
Components embedded in the vesicles will continue to diffuse and this property makes this surface ideal for membrane bound receptor studies – 由于嵌入在囊泡中的成分继续弥散,可作为理想的膜表面受体研究的化学修饰表面
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Gold Only(纯金)
Bare gold surface with no modifications – 没有任何化学修饰的纯金表面
Used primarily where the customer wants to utilize their own surface chemistry and immobilization techniques – 主要适用于客户希望运用自行设计的表面化学修饰和键合技术