化合物N-Nornuciferine hydrochloride TQ0296L

Product Introduction
Bioactivity


英文名: N-Nornuciferine hydrochloride(4846-19-9 free base)

描述: N-Nornuciferine hydrochloride(4846-19-9 free base) (N-Nornuciferine hydrochloride) 是荷叶中的一种 aporphine 生物碱，显着抑制 CYP2D6（IC50：3.76 μM，Ki：2.34 μM）。

体外活性: N-Nornuciferine 强烈抑制 CYP2D6 活性，但对其他四种 P450 异构酶（CYP2C19, CYP3A4, CYP2E1, CYP2C9）表现出弱抑制或无抑制作用。N-Nornuciferine 以竞争性方式抑制 CYP2D6 催化的右美沙芬 O-去甲基化（Ki: 2.34 μM）。

存储条件: keep away from direct sunlightPowder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 25 mg/mL (78.66 mM)


关键字: NNornuciferine hydrochloride(4846199 free base) | N-Nornuciferine Hydrochloride | N Nornuciferine hydrochloride(4846 19 9 free base)

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