图1 RRBS测序reads的特征和质量 参考文献 [1] Jia et al. Negative regulation of DNMT3A de novo DNA methylation by frequently overexpressed UHRF family proteins as a mechanism for widespread DNA hypomethylation in cancer.Cell Discovery, 2016. [2] Chatterjee et al. Genome-scale DNA methylome and transcriptome profiling of human neutrophils. Scientific Data, 2016.