Steinernema kraussei线虫在高分辨率共焦拉曼中的成像

简介：
• Nematodes are key model organisms for understanding the functions of genes and proteins, and human diseases, such as HIV and Alzheimer’s Disease
• Genotype-phenotype investigation in genetically modified nematodes has provided important information on gene and protein functions
• Current biological assays mostly rely on using stains, dyes or labels, and/or invasive techniques
• For the first time, Raman spectroscopic imaging has been explored as a tool for analysing a nematode, non-invasively and without labelling
• inVia's StreamLine imaging reveals chemico-structural information of the imaged area at high spatial resolution
• The resultant images provide a powerful and visual method for assessing phenotypic changes in nematodes at the sub-micrometre scale