毛细管流体动力分馏（CHDF）的分辨率和适用性研究进展

Abstract

Capillary Hydrodynamic Fractionation (CHDF) is a high-resolution particle size distribution (PSD) analysis technique. CHDF is used to measure the PSD of colloids in the particle size range of 5 nm to 3 microns.

CHDF fractionation occurs as an eluant or carrier fluid carries the particles downstream in a capillary tube. Large particles exit the fractionation capillary ahead of smaller particles. Particle fractionation occurs because of the combination of the eluant parabolic velocity profile (laminar flow), size exclusion of the particles at the capillary wall, and colloidal forces.

The aim of this study was to expand CHDF’s applicability to a broader class of colloidal systems. This can widen CHDF’s usefulness as a particle sizing technique.

摘要：

毛细管流体动力分馏（CHDF）是一种高分辨率粒度分布（PSD）分析技术。CHDF用于测量粒径范围为5 nm至3微米的胶体的粒度分布。

CHDF分馏发生在洗脱液或载液将颗粒携带到毛细管下游时。大颗粒在小颗粒之前离开分馏毛细管。由于洗脱液抛物线速度分布（层流）、毛细管壁上颗粒的尺寸排除和胶体力的组合，颗粒分馏发生。

本研究的目的是将CHDF的适用范围扩展到更广泛的胶体系统，这可以扩大CHDF作为粒度技术的用途。