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使用串联质谱法和自动在线样品制备技术定量抗抑郁药和抗精神病药 |
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前言:
Liquid chromatography-mass spectrometry (LC/MS) is a powerful technique applied in clinical research for the analysis of a broad number of analytes. Offline sample preparation techniques (solid phase extraction and liquid-liquid extraction) are widely used but are often time consuming and labor intensive. The Thermo Scientific Transcend system powered by TurboFlowTM technology provides an alternative approach simplifying sample preparation.
仪器:
Thermo Scientific TSQ Quantum mass spectrometer
结论:
A fast and analytically sensitive method for the detection of 18 antidepressants and neuroleptics is described. The Transcend TLX automated online sample preparation system allows minimal sample preparation and time saving in the absence of SPE sample preparation for clinical research laboratories.