Latest Advances in the Analysis of Volatile Organic Compounds by Single Quadrupole GC-MS

　　Introduction

　　A method was developed for the analysis of volatile organic compounds (VOCs) with the Thermo Scientific ISQ single quadrupole GC-MS using quality control requirements based on United States Environmental Protection Agency (EPA) methodologies. This requires integration of a range of instrumentation, from the sample introduction system to the gas chromatograph and mass spectrometer, to the software for data interpretation,analysis and reporting.¹ While the overall process of analyzing VOC is a mature technique, there are continuous innovations that allow laboratories to meet lower detection limits and analyze new compounds to comply with changing regulations, with higher throughput and improved quality.