应用QED技术,采用EQuan与三重四级杆LC-MS联合分析水中杀虫剂

　　Abstract：

　　In recent years, the use of LC-MS/MS for pesticide analysis has become increasingly popular due to the amenability of electrospray ionization (ESI) for polar compounds. This application note describes the Multi-residue assay of a group of pesticides in drinking water by EQuan. The method utilizes SRM for Quantification, followed by Data Dependent™ QED MS/MS and library searching for the structural confirmation of these analytes.

　　Traditionally, water samples are extracted in a very time consuming manner, using 1 L of sample that is concentrated 100-1000 times before analysis. This extraction can take several hours or even days of preparation time. Also, the added expense of extraction cartridges leads to more expense per sample for labs. EQuan is a solution that allows for automated online preconcentration of samples without the need for extensive

　　Instrument：

　　TSQ QUANTUM系列LC/MS液质联用系统

　　Equan环境定量系统

　　Conclusion：

　　The Quantitation Enhanced Data Dependent scan function,standard on all TSQ Quantum mass spectrometers, allows the user to obtain confirmatory data following quantitative analysis. This is of particular significance when analyzing environmental pollutants in water samples. EQuan, with its large injection volume, allows for significant time savings over traditional SPE concentration methods, and allows for detection and quantitation of compounds at levels well below the regulatory requirements.

　　Thermo Scientific’s built in library of over 1000 compounds in the industry standard NIST format can help users to positively identify compounds based on EU regulations. Additionally, users have the ability to add to or replace the spectra in the library to increase their positive hit probabilities when searching the library.