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工商注册信息已核实!领域: | 细胞生物学,分子生物学,蛋白/抗体/蛋白质组,多组学/蛋白质组/代谢组/脂质组,生物制药/仿制药 | ||
样品: | lipid | 项目: | untargeted 4D lipidomics LC-MS/MS workflows |
参考: | - |
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Using Parallel Accumulation Serial Fragmentation (PASEF) to speed up untargeted 4D lipidomics LC-MS/MS workflows |
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The search for new and validated biomarkers is of particular interest in clinical areas like oncology or neurology. As lipids play an important role in many diseases, the area of lipidomics has become central for clinical research.
Introduction
While commonly an in-depth oriented approach to ID as many lipids as possible is applied, clinically-oriented projects demand a high throughput for large sample cohorts. Therefore, a short cycle time per sample is necessary to realize research projects with hundreds or even thousands of samples in a reasonable time frame. To enable this, the analytical instrumentation needs to deliver an uncompromised high data quality at high acquisition speeds. This is realized by the PASEF (Parallel Accumulation Serial Fragmentation) acquisition mode on the timsTOF Pro system.