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Analysis of metabolic changes in murine hair follicles treated with Procyanidin-B2 rich nutraceuticals by DI-MRMS
发布时间:2019-06-26
Known for anti-inflammatory and antioxidant properties, nutraceuticals enriched in Procyanidin-B2 promote hair growth both in vitro and in vivo. Howev
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Glycan Sequencing by Electronic Excitation Dissociation Tandem Mass Spectrometry
发布时间:2019-06-26
Glycoconjugate glycans play vital roles in a wide range of physiological and pathological processes, such as embryogenesis, host-pathogen interactions
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MLKL Activation and Oligomerisation analysis using cross-linking LC-MS and Native Mass Spectrometry
发布时间:2019-06-26
This study utilized multiple mass spectrometry techniques to characterise necroptotic cell death which is mediated by the pseudokinase, mixed lineage
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Using Parallel Accumulation Serial Fragmentation (PASEF) to speed up untargeted 4D lipidomics LC-MS/MS workflows
发布时间:2019-06-05
The search for new and validated biomarkers is of particular interest in clinical areas like oncology or neurology. As lipids play an important role i
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Parallel accumulation - serial fragmentation combined with data-independent acquisition (diaPASEF)
发布时间:2019-06-05
The timsTOF Pro with diaPASEF enables deeper proteome coverage in a single 4D shotgun proteomics experiment, with highly reproducible qualitative and
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Novel MALDI Imaging solution empowered by a timsTOF fleX and dedicated bioinformatics pipeline for identification of lipids from tissue
发布时间:2019-06-05
MALDI Imaging spectra can be used to investigate how compounds are localized across tissue samples. In this application note, we present a novel softw
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High Speed, High Lateral Resolution Lipid Imaging using a timsTOF fleX
发布时间:2019-06-05
High Speed, High Lateral Resolution Lipid Imaging using a timsTOF fleXChanges in lipid profiles are known to occur in response to stress and disease.T
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Proteomic changes in tissue samples of mouse gastric carcinoma: Label-free quantitation on the timsTOF fleX with PASEF
发布时间:2019-06-05
timsTOF fleX with PASEF enables deeper proteome coverage in shortest possible time, always with high sensitivity and robustness.AbstractThe timsTOF fl
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组学研究加速生化制品生产效率
发布时间:2019-03-22
通过impact II Q-TOF 质谱进行蛋白组学和代谢组学研究,可以深入观察到合理的菌种如何设计提高了生物生产效率。基于代谢组学和蛋白组学的组学研究,可以找到精氨酸合成途径改变的理由和解决生化合成途径存在的瓶颈。了解更多前沿应用,请关注
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非监督的MS/MS二级谱图的相似性代谢轮廓图分析显示与防御有关的土豆代谢物
发布时间:2019-03-06
Solanum tuberosum (potato) wildtype and overexpression lines with an enhanced Phytophtora infestans resistance were analysed for their metabolic respo
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质谱成像进行草莓中花青素分布分析
发布时间:2019-03-05
MALDI TOF 质谱成像可早广泛的分子质量范围内同时检测和定位分子种类,在生物样品中,多种类别的生物分子可被找到,包括代谢物,糖,脂质,肽段和蛋白质。本实验中,花青素通过布鲁克MALDI TOF 质谱系统在草莓中被快速检测并定位到。详情请下载应用文献。布鲁克微信
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2018布鲁克MRMS及质谱成像用户研讨会
发布时间:2018-09-05
2018布鲁克MRMS及质谱成像用户研讨会(第一轮通知)布鲁克极限分辨率技术又一次革命性提升,帮助科研工作者突破科学的疆域,看到 “隐藏的信息”,达到从结构到功能的转变。布鲁克将携手南京师范大学,于2018年12月13日在南京举办2018年布鲁克MRMS及质谱成像用户研讨会,本次会议将邀请众多国内外
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磁共振质谱MRMS自动化批量鉴定临床样本中的生物标志物
发布时间:2018-08-27
在临床体液样本如血清和尿液分析中,磁共振质谱MRMS的高质量精度和超高分辨率结合MALD离子化可以提高样本分析速度和对数据直接评价,而无需繁琐的样本制备或纯化。自动MALDI MRMS 通过最简单的样品制备和批量数据采集及处理方法,满足了临床分析大样本量高通量的要求,提供了大样本组的补充信息支持NM
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MRMS aXelerate 解决方案快速测定白杨树叶中微污染物和植物响应代谢物
发布时间:2018-08-13
MRMS aXelerate方案被证明是一个有效的新工作流程,可以应对环境污染情况下的植物成分的快速检测。这项技术不经色谱分离,通过流动注射分析(FIA)结合scimaX磁共振质谱系统(MRMS)提供的超高质量分辨率来提高分析速度或样品通量。MRMS aXelarate方案中MetaboScape
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烟草Nicotiana attenuata在感染真菌Rhizophagus irregularis时的代谢反应的分析表征
发布时间:2018-02-09
Exploring the chemical composition of plants is challenging. It is highly dynamic and can be modified by many environmental factors. Knowledge of this
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Mapping of Greek olive oil
发布时间:2018-01-10
In this study, LC free magnetic resonance mass spectrometry (MRMS) analysis was employed for mapping and quality control assessment of Greek extra vir
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Using Ion Mobility to separate different designer drug metabolites
发布时间:2018-01-09
The large number of new emerging designer drugs and the need to detect not only the parent analyte but their metabolites poses a big challenge in fore
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High-performance MALDI imaging analysis of on-tissue digested proteins in mammalian FFPE tissues
发布时间:2018-01-04
In this application note, we describe a workflow for MALDI Mass Spectrometry Imaging (MSI) of proteins from a variety of FFPE tissues. The method comp
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Software Assisted Data Mining Strategies to Identify Metabolites of New Psychoactive Substances with LC-QTOF MS
发布时间:2017-10-24
• Mass-MetaSite™ software and the described workflow proved to be a suitable, less laborious and time consuming procedure compared to manual data eval
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Characterization of petroleum samples via thermal analysis coupled to APCI FTMS
发布时间:2017-10-24
Thermal analysis coupled to ultra-high resolution mass spectrometry enables the detailed temperature resolved chemical characterization of the evolved