PASEF™ on a timsTOF Pro defines new performance standards for shotgun proteomics with dramatic improvements in MS/MS data acquisition rates and sensitivity

领域：蛋白/抗体/蛋白质组    样品：A complex tryptic peptide mixture derived from HeLa cells    项目： MS    参考：[1] Meier, et al. (2015) Mol Cell Proteomics. 14(7):2014-29. [3] Lubeck et al. Poster presented at: 65th ASMS Conference on Mass Spectrometry and Allied Topics, June 6, 2017; Indianapolis, IN.   

Trapped ion mobility spectrometry coupled with quadrupole time-of-flight mass spectrometry (timsTOF Pro) offers a unique dimension of characterization and separation in complex mixtures. The timsTOF Pro instrument also enables the previously introduced  “Parallel Accumulation Serial Fragmentation” (PASEF) method.