A heterocyclic polar solvent and polymer precursor.
Tetrahydrofuran (THF) is a saturated cyclic ether that is mainly used as an organic solvent. When stored for a long time, it forms organic peroxides. This process can be inhibited by adding butylhydroxytoluene (BHT) as a stabilizer. BHT removes free radicals needed to form peroxides. It is a key fragment of various natural products (polyether antibiotics). THF can form double hydrates with hydrogen sulfide, and its crystal structure has been studied by three-dimensional single crystal method. Application: Dried tetrahydrofuran (THF) has been used to synthesize dichloride {bis [1,1 ',1 "-(phosphine triyl) tripiperidine] palladium [(P(NC5H10)3)2Pd(Cl)2], which is widely used as a catalyst in Heck reactions. It has been used as a Heck cross-coupling reaction medium for various aryl bromine and olefin.