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样品: | 美托洛尔 | 项目: | 分析美托洛尔及选定的杂质组分 |
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结合紫外和电雾式检测器亲水作用色谱分析美托洛尔及选定的杂质组分 |
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A simple, rapid, and accurate method without derivatization was developed for the analysis of metoprolol succinate and metoprolol EP impurity A, M, and N using isocratic HILIC chromatography with UV and charged aerosol detection. The HPLC detectors are orthogonal and complimentary in nature and render a more comprehensive analysis of the sample since they can detect both chromophore and non-chromophore species using the configuration described. The integrated Vanquish system provides excellent data quality.