Prof. Ge Ying：用尖端质谱打造Top-Down蛋白质组学前沿技术

Withover 70 peer-reviewed publications to her name, Professor Ying Ge is an established leader in the field of proteomics with a special focus on cardiovascular systems biology.

The Ge lab at UW-Madison aims to understand the molecular and cellular mechanisms underlying cardiovascular diseases via systems biology approaches featuring cutting-edge high-resolution mass spectrometry (MS)-based comparative proteomics and metabolomics in conjunction with biochemical/ biological/ physiological functional studies.

Professor Ge’s lab use three key instruments for top-down proteomics: the solariX XR™ FTMS, Maxis II and Impact II Q-TOF, each of which provides different benefits for her work. Professor Ge used Fourier Transfer mass spectrometry (FTMS), and the ultra-high resolution and high sensitivity still makes it the best instrument for characterizing large proteins through a top-down approach, and differentiates it from other mass spectrometers currently in use on the UW-Madison campus. Professor Ge uses this instrument for translational and clinical research to understand the basis of human diseases, as well as identifying potential molecular biomarkers for treatment of disease.